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期刊信息:
《药学服务与研究》2017年, 第17卷, 第6期, 第453-456页
标题:
药物性急性间质性肾炎的病例报告及文献分析
DOI:
10.5428/pcar20170616
作者:
1. 陈莹1(1.武汉大学人民医院药学部 武汉 430060 [email protected])
2. 何娟2(2.上海交通大学医学院附属瑞金医院药学部 上海 200025 )
3. 宋金春1(1.武汉大学人民医院药学部 武汉 430060 )
4. 景峰3(3.上海交通大学医学院附属瑞金医院急诊重症医学科 上海 200025 [email protected])
摘要:
摘要  目的:探讨药物相关急性间质性肾炎(drug-induced acute interstitial nephritis,DAIN)的临床特征、危险因素、预防和治疗对策。方法:报道抗菌药物致急性间质性肾炎(acute interstitial nephritis,AIN)的病例,并进行相关文献分析。结果和结论:多种抗菌药物均可导致DAIN,万古霉素是最常见的药物之一。DAIN最典型的临床症状有发热、皮疹、嗜酸性粒细胞增多、尿常规异常和肾功能损伤。DAIN的预防应做到不滥用抗菌药物,减少不必要的联合用药;使用有肾毒性药物时,应定期监测血药浓度和肾功能。治疗原则包括及早诊断、及时停用可疑药物,对于重症病例宜给予糖皮质激素治疗。
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若需在您的论文中引用此文,请按以下格式著录参考文献:
中文著录格式 陈莹1,何娟2,宋金春1,景峰3. 药物性急性间质性肾炎的病例报告及文献分析[J]. 药学服务与研究. 2017; 17(6): 453-456.
英文著录格式 CHEN Ying1,HE Juan2,SONG JinChun1,JING Feng3. Drug-induced acute interstitial nephritis: case report and literature review[J]. Pharmaceutical Care and Research / yao xue fu wu yu yan jiu. 2017; 17(6): 453-456.
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