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期刊信息:
《药学服务与研究》2018年, 第18卷, 第2期, 第92-95页
标题:
盐酸托莫西汀对注意缺陷多动障碍患儿生活质量的研究
DOI:
10.5428/pcar20180203
作者:
1. 赵泾泾(第二军医大学长征医院儿科 上海 200003 [email protected])
2. 徐通(第二军医大学长征医院儿科 上海 200003 [email protected])
3. 周翊(第二军医大学长征医院儿科 上海 200003 )
4. 帅瑞雪(第二军医大学长征医院儿科 上海 200003 )
5. 张彩英(第二军医大学长征医院儿科 上海 200003 )
6. 王德凤(第二军医大学长征医院儿科 上海 200003 )
摘要:
摘要  目的:观察盐酸托莫西汀对注意缺陷多动障碍(attention deficit hyperactivity disorder,ADHD)患儿生活质量的影响。方法:选取2016年9月至2017年9月就诊于第二军医大学长征医院儿科ADHD专科门诊,并确诊的ADHD患儿62例,32例予服用盐酸托莫西汀治疗6个月(治疗组),30例暂不服药的患儿作为对照组。采用SNAP-Ⅳ量表和CHIP-CE量表考察盐酸托莫西汀对患儿症状和生活质量的影响。分别在治疗前(基线)、治疗2个月和治疗6个月进行问卷调查评估。结果:治疗前两组患儿一般资料、SNAP-Ⅳ评分和CHIP-CE评分无统计学差异(P>0.05)。经盐酸托莫西汀治疗后,治疗组患儿SNAP-Ⅳ评分显著下降,CHIP-CE评分显著升高,与对照组比较有统计学差异(P<0.01)。结论:盐酸托莫西汀可以显著改善ADHD患儿的症状和生活质量。
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若需在您的论文中引用此文,请按以下格式著录参考文献:
中文著录格式 赵泾泾,徐通,周翊,帅瑞雪,张彩英,王德凤. 盐酸托莫西汀对注意缺陷多动障碍患儿生活质量的研究[J]. 药学服务与研究. 2018; 18(2): 92-95.
英文著录格式 ZHAO JingJing,XU Tong,ZHOU Yi,SHUAI RuiXue,ZHANG CaiYing,WANG DeFeng. Study on the life quality of children with attention deficit hyperactivity disorder treated with atomoxetine hydrochloride[J]. Pharmaceutical Care and Research / yao xue fu wu yu yan jiu. 2018; 18(2): 92-95.
参考文献:
1. Peasgood T,Bhardwaj A,Biggs K,et al.The impact of ADHD on the health and well-being of ADHD children and their siblings[J].Eur Child Adolesc Psychiatry,2016,25(11):1217-1231.
2. Hutchison S L,Ghuman J K,Ghuman H S,et al.Efficacy of atomoxetine in the treatment of attention-deficit hyperactivity disorder in patients with common comorbidities in children, adolescents and adults:a review[J].Ther Adv Psychopharmacol,2016,6(5):317-334.
3. Harvey E A,Breaux R P,Lugo-Candelas C I.Early development of comorbidity between symptoms of attention-deficit/hyperactivity disorder (ADHD) and oppositional defiant disorder (ODD)[J].J Abnorm Psychol,2016,125(2):154-167.
4. Montoya A,Quail D,Anand E,et al.Prognostic factors of improvement in health-related quality of life in atomoxetine-treated children and adolescents with attention-deficit/hyperactivity disorder,based on a pooled analysis[J].Atten Defic Hyperact Disord,2014,6(1):25-34.
5. Banaschewski T,Johnson M,Lecendreux M,et al.Health-related quality of life and functional outcomes from a randomized-withdrawal study of long-term lisdexamfetamine dimesylate treatment in children and adolescents with attention-deficit/hyperactivity disorder[J].CNS Drugs,2014,28(12):1191-1203.
6. Wang L J,Chen C K,Huang Y S.Neurocognitive performance and behavioral symptoms in patients with attention-deficit/hyperactivity disorder during twenty-four months of treatment with methylphenidate[J].J Child Adolesc Psychopharmacol,2015,25(3):246-253.
7. Galloway H,Newman E.Is there a difference between child self-ratings and parent proxy-ratings of the quality of life of children with a diagnosis of attention-deficit hyperactivity disorder (ADHD)? A systematic review of the literature[J].Atten Defic Hyperact Disord,2017,9(1):11-29.
8. Jonsson U,Alaie I,Lfgren Wilteus A,et al.Annual research review: quality of life and childhood mental and behavioural disorders-a critical review of the research[J].J Child Psychol Psychiatry,2017,58(4):439-469.
9. Coghill D R,Banaschewski T,Soutullo C,et al.Systematic review of quality of life and functional outcomes in randomized placebo-controlled studies of medications for attention-deficit/hyperactivity disorder[J].Eur Child Adolesc Psychiatry,2017,26(11):1283-1307.
10. Marques J C,Oliveira J A,Goulardins J B,et al.Comparison of child self-reports and parent proxy-reports on quality of life of children with attention deficit hyperactivity disorder[J].Health Qual Life Outcomes,2013,11(1):186.
11. Coghill D,Hodgkins P.Health-related quality of life of children with attention-deficit/hyperactivity disorder versus children with diabetes and healthy controls[J].Eur Child Adolesc Psychiatry,2016,25(3):261-271.
12. 张跃兵,李荣琴,王爱芹,等.注意缺陷多动障碍儿童的生活质量及相关因素分析[J].中国儿童保健杂志,2016,24(8):804-806,813.
13. YU Guo,LI GuoFu,Markowitz J S.Atomoxetine:a review of its pharmacokinetics and pharmacogenomics relative to drug disposition[J].J Child Adolesc Psychopharmacol,2016,26(4):314-326.
14. Hutchison S L,Ghuman J K,Ghuman H S,et al.Efficacy of atomoxetine in the treatment of attention-deficit hyperactivity disorder in patients with common comorbidities in children,adolescents and adults:a review[J].Ther Adv Psychopharmacol,2016,6(5):317-334.